How genetic diseases affect the human body! Some diseases run in families and scars the line of upcoming generations, due to which it creates a rift between the healths of individuals. These diseases are known as genetic diseases, which travel from parent to child. Genetic diseases can cause a disbalance as the defective genes invade the body and create various complications. These diseases target major organs whose survival is necessary for the human body. The human body functions like a machine, just like a machine works on the functions run by the parts. Just like that, a human body also needs intact management of bodily functions. The bodily functions usually run if no complication is created by any disease, foreign infection, or viruses. The primary cause of genetic disorders is the abnormality of the genes. The typical sequence of the DNA is disrupted as mutations in the genes occur and cause genetic disorders. Most of the diseases have a genetic component; parents carrying the defective genes can increase the risk for the child to inherit the mutated genes. Many organs become a target of these genetic mutations as the disease caused by them can damage and cause further obstructions. One of the fatal genetic disorders that target the major organs and creates life-threatening issues is polycystic kidney disease. What is polycystic kidney disease? Polycystic kidney disease is a genetic kidney disorder that causes sacs filled with fluids in the kidneys. The kidneys are said to be the balance of the human body. As they perform multiple duties and handle them as per the body's requirement. They balance electrolytes, manage blood pressure, and most importantly, these bean-shaped organs are responsible for filtering the blood and eliminating the waste products from the body. The cysts of PKD are dangerous as they begin to spread their maliciousness from the structural and functional units of the kidneys (nephrons). The growth of cysts causes enlargement of kidneys and affects the rate of functioning of the kidneys. Considerable growth of cysts can prove to be harmful to the kidneys. Obstructions in blood filtration, reabsorption of essential substances, elimination of waste products occur due to which waste products and excess fluids accumulate in the blood. The progression of polycystic kidney disease depends on the rate of growth of cysts. These cysts can also metastasize to other parts of the body, like the liver. However, It is reliable to say that Polycystic kidney disease damages kidneys and surrounding organs can also face issues running their daily functions. This genetic disorder can welcome a fatal major kidney disease if it reaches its extremity. Chronic kidney disease occurs when kidneys start losing their functionality over time due to PKD cysts. So we can say that PKD is a form of CKD (chronic kidney disease) as the kidney loses function over time in both diseases. Difference between renal cysts and PKD cysts People often get confused after hearing the word cyst. They assume that simple renal cysts and PKD cysts are the same. But there is a difference between them. Their names are the same, but their motives are not. The cysts of PKD can cause a strike of complications and impairs kidney function by changing their structure and damaging their functional parts. Unlike PKD cysts, simple renal cysts do not cause impaired kidney function or enlargement of the kidneys. What are the types of polycystic kidney disease? Polycystic kidney disease ayurvedic treatment depends on the cause of the disease as causes are the foundation of the disease and build the passage for the disease to enter the body. The cause of PKD also depends on the form of PKD. Two main types of PKD are as follows: 1. Autosomal dominant polycystic kidney disease (ADPKD). 2. Autosomal recessive polycystic kidney disease (ARPKD). What causes Polycystic kidney disease? The mutations in the genes cause polycystic kidney disease. Sometimes a gene mutation occurs on its own, which is known as spontaneous gene mutation. The two main types of PKD define the causes of the disease more clearly. ● Autosomal dominant polycystic kidney disease: This type of PKD accounts for most of the cases. It causes cysts in the kidneys only. The signs and symptoms appear between the age group of 30 - 40. One parent with the defective gene can transfer the disease to the child. The child can inherit the kidney disorder with the chances of 50%. ● Autosomal recessive polycystic kidney disease: This type of PKD is not that common as ADPKD. The growth of cysts in ARPKD spreads in both kidneys and the liver. Signs and symptoms become noticeable shortly after birth, or some cases do not experience symptoms until late childhood or during adolescence. Both the parents must be having defective genes in order to transfer this type of PKD. Each child will procure 25% chances to inherit the kidney disorder. What are the symptoms of polycystic kidney disease? The detection of symptoms is associated with the growth of cysts in the kidneys. When kidneys become unable to perform their duties, certain complications arise and causes symptoms that include: ● Abdominal pain. ● Bloody urine. ● Frequent urges to urinate. ● Side pain. ● Urinary tract infection (UTI). ● Kidney stones. ● Sensitive skin that bruises easily. ● Back pain. ● Unusual pale skin color. ● Fatigue. ● Joint pain. ● Nail abnormalities. Children suffering from autosomal recessive polycystic kidney disease can have symptoms like: ● High blood pressure or hypertension. ● Urinary tract infection. ● Frequent urination. What complications are triggered by polycystic kidney disease? Several complications arise when kidneys fall to the verge of losing their functionalities. These underlying complications can be controlled with the help of Polycystic kidney disease ayurvedic treatment. ● Kidney failure or End-stage renal disease (ESRD): It is the last and severe chronic kidney disease stage. The progression of the PKD can cause impaired kidney function that worsens over time and leads to the life-threatening outcome of kidney failure. ● High Blood pressure: One of the functions of the kidneys is to manage blood pressure. When PKD strikes, the kidneys don't function normally, which results in high blood pressure. Poor control of blood pressure can cause further damage to the kidneys. ● Persistent pain: Side and back pain occurs in people with polycystic kidney disease. ● Growth of cysts: These cysts can damage the surrounding organs also. The cysts can spread in the liver and cause further obstruction in other bodily functions also. ● Brain aneurysms: Bulge shaped like a balloon in the blood vessel named aneurysm can cause internal bleeding after it ruptures. ● Pregnancy complications: Pregnant women can develop preeclampsia and high blood pressure if they have impaired kidney function. ● Heart valve abnormalities. ● Colon problems. How is polycystic kidney disease diagnosed? If you have a family history or you experience symptoms of polycystic kidney disorder. Then the doctor will review the family history by genetic testing. Other tests would be performed to look for anemia, blood, or protein in the urine. Imaging tests that diagnose polycystic kidney disease are: ● Abdominal ultrasound. ● Abdominal CT scan. ● Abdominal MRI scan. ● Intravenous pyelogram. Can ayurvedic treatment reduce the progression of PKD? Ayurveda includes the ancient medical treatment methods that have acquired significant experience and expertise in the matters of human anatomy. Ayurvedic theories have proven to treat even major kidney diseases like polycystic kidney disease. The holistic and authentic approach to natural treatment does not rely on dialysis or renal transplants. Polycystic kidney disease ayurvedic treatment defies the use of drug-based medications and prescribes herb-based medications instead. As ayurvedic herbs that are kidney-friendly can help reduce the progression of the disease and the rate of growth of cysts in the kidneys. These herbs are natural and do not cause any type of side effects on the body's natural healing capabilities. A diet chart is also customized according to the reports and contains superfoods that boost your metabolism and immune system to fight kidney disease. However, Polycystic kidney disease ayurvedic treatment can help in reducing the progression of the genetic kidney disorder by using all-natural and effective options. The limit of Ayurveda can go from treating the disease from the core to curing it. The treatment is affordable and enhances your mental and physical state.